Key result
A history of Kawasaki disease was not associated with a significantly increased mortality rate compared to the general population (SMR 1.25; 95% CI 0.84-1.85).
Why the study?
Do patients with a history of Kawasaki disease have a higher death rate than an age-matched healthy population?
Population
6,576 patients with a new definite diagnosis of Kawasaki disease in Japan
Design
Cohort
Follow-up
Up to 17.5 years (enrolled 1982-1992, followed until 1999)
Authors
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Reassures on overall post-acute mortality after Kawasaki disease; leaves open potential subgroup risks in males with cardiac sequelae.
Cohort (n=6,576)
Yes
Do patients with a history of Kawasaki disease have a higher death rate than an age-matched healthy population?
Effect estimate: SMR 1.25 (95% CI 0.84-1.85)
Mortality rates for patients with a history of Kawasaki disease are generally not elevated after the acute phase, though male patients with cardiac sequelae may have a higher risk.
Nakamura et al. (2002) conducted a cohort in Kawasaki disease (n=6,576). History of Kawasaki disease vs. Age-matched healthy population (Japanese vital statistics) was evaluated on Mortality (SMR 1.25, 95% CI 0.84-1.85). A history of Kawasaki disease was not associated with a significantly increased mortality rate compared to the general population (SMR 1.25; 95% CI 0.84-1.85).
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