Key result
Diabetes mellitus, hypertension, and older age were independently associated with orthostatic hypotension, which was present in 16.3% of the community-dwelling population.
Why the study?
What factors are independently associated with orthostatic hypotension in a community-dwelling Chinese population in Taiwan?
Cross-Sectional (n=728)
What factors are independently associated with orthostatic hypotension in a community-dwelling Chinese population in Taiwan?
Age, hypertension, and diabetes mellitus are independent risk factors for orthostatic hypotension in community-dwelling individuals, highlighting the need for regular supine and upright blood pressure monitoring in these groups.
Supports consideration of orthostatic BP checks in older adults with diabetes or hypertension; leaves open whether screening improves outcomes.
Factors associated with orthostatic hypotension are heterogeneous, and some of the factors are interrelated and interdependent, which may confound their relationships to orthostatic hypotension. To investigate the factors that were most likely related to orthostatic hypotension, a study of community-dwelling persons (419 men and 309 women) was conducted. Blood pressures and heart rates were measured after the subjects had been recumbent for 5 min and upright for 1 min. A total of 119 persons (16.3%) experienced orthostatic hypotension. Univariate analysis showed that orthostatic hypotension was associated with the following variables: hypertension, diabetes mellitus, cerebrovascular disease, proteinuria, abnormal renal function, or medications use. Those patients with orthostatic hypotension were older in age and had a higher body mass index, seated blood pressure, plasma creatinine, hemoglobin A1c, fasting and 2-h postload glucose levels than those without orthostatic hypotension. Multivariate analysis revealed that diabetes mellitus, hypertension, and age were independently associated factors for orthostatic hypotension. The higher the level of plasma hemoglobin A1c (%) elevation, the higher the likelihood of orthostatic hypotension manifestation. Clinically, elderly persons or patients with hypertension or diabetes mellitus should receive regular monitoring of supine and upright blood pressure in order to detect orthostatic hypotension and prevent its complications.
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Wu et al. (1996) conducted a cross-sectional in Orthostatic hypotension (n=728). Diabetes mellitus, hypertension, and age vs. Absence of these risk factors was evaluated on Orthostatic hypotension. Diabetes mellitus, hypertension, and older age were independently associated with orthostatic hypotension, which was present in 16.3% of the community-dwelling population.
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