Key result
Serum digoxin level measurement and acetyl strophanthidin tolerance testing yielded discordant results in 42% of titrations among patients on maintenance digoxin.
Why the study?
How does acetyl strophanthidin tolerance testing compare with serum digoxin level measurement in assessing the degree of digitalization in patients on maintenance digoxin?
Population
133 patients with diverse cardiac disorders receiving maintenance digoxin
Comparison
Acetyl strophanthidin tolerance testing vs Serum digoxin level (SDL) measurement
Design
Cross-sectional
Authors
Loading...
May warrant caution relying solely on serum digoxin levels; leaves open whether tolerance testing refines dosing in maintenance therapy.
Observational (n=133)
How does acetyl strophanthidin tolerance testing compare with serum digoxin level measurement in assessing the degree of digitalization in patients on maintenance digoxin?
Acetyl strophanthidin titration testing frequently yields discordant results compared to serum digoxin levels, suggesting it may provide additional insight into optimal therapeutic glycoside dosing, especially in patients with severe valvular disease or advanced age.
Klein et al. (1974) conducted an observational in Diverse cardiac disorders (n=133). Serum digoxin level measurement vs. Acetyl strophanthidin tolerance testing was evaluated on Discordant results between serum digoxin levels and acetyl strophanthidin tolerance. Serum digoxin level measurement and acetyl strophanthidin tolerance testing yielded discordant results in 42% of titrations among patients on maintenance digoxin.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: