Why the study?
Does acute intravenous ouabain improve hemodynamics in symptomatic patients with pure mitral stenosis in normal sinus rhythm or atrial fibrillation?
Population
11 symptomatic patients with pure mitral stenosis (8 in normal sinus rhythm and 3 in atrial fibrillation)
Comparison
Acute intravenous administration of ouabain vs Baseline at rest and during moderate and intense…
Design
Case_series
Authors
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No hemodynamic benefit in sinus rhythm; leaves open digitalis role in mitral stenosis.
Does acute intravenous ouabain improve hemodynamics in symptomatic patients with pure mitral stenosis in normal sinus rhythm or atrial fibrillation?
Acute intravenous ouabain provides no hemodynamic benefit to symptomatic patients with pure mitral stenosis in normal sinus rhythm, challenging the routine use of digitalis in this population.
BEISER et al. (1968) studied this question.
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