Key result
Octogenarians undergoing PCI face ~13% 1-year mortality, largely predicted by cardiogenic shock and diabetes.
Why the study?
Trends in patient characteristics and clinical outcomes over time, as well as predictors of mortality, needed examination in octogenarians undergoing PCI.
What are the clinical outcomes and predictors of mortality in octogenarians undergoing percutaneous coronary intervention?
Observational (n=782)
No
What are the clinical outcomes and predictors of mortality in octogenarians undergoing percutaneous coronary intervention?
PCI is a safe and effective revascularization method for appropriately selected octogenarians, demonstrating acceptable complication rates even in settings without on-site surgical support.
Answers are grounded in this paper and cite their sources.
May inform risk stratification in octogenarian PCI; leaves open prospective validation of predictors.
OBJECTIVE: To examine the trends in patient characteristics and clinical outcomes over a ten-year period and to analyse the predictors of mortality in octogenarians undergoing percutaneous coronary intervention (PCI) in our centre. METHODS: A total of 782 consecutive octogenarians (aged 80 and above) were identified from a prospectively collected PCI database within our non-surgical, medium volume centre between 1st January 2007 and 31st December 2016. This represented 10.9% of all PCI procedures performed in our centre during this period. We evaluated the demographic and procedural characteristics of the cohort with respect to clinical outcomes (all-cause in-hospital and 1-year mortality, in-hospital complication rates, duration of hospital admission, coronary disease angiographic complexity and major co-morbidities). The cohort was further stratified into three chronological tertiles (January 2007 to July 2012, 261 cases; August 2012 to May 2015, 261 cases; June 2015 to December 2016, 260 cases) to assess for differences over time. Predictors of mortality were identified through a multivariate regression analysis. CONCLUSION: This contemporary observational study provides a useful insight into the real-world practice of PCI in octogenarians.
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Abramik et al. (2022) conducted an observational in Coronary artery disease requiring PCI (n=782). Percutaneous coronary intervention was evaluated on 1-year mortality. In octogenarians undergoing percutaneous coronary intervention, the 1-year mortality rate was 13.0%, with cardiogenic shock, severe left ventricular impairment, and diabetes identified as strong independent predictors of mortality.
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