Why the study?
Does reduced blood flow via NOS and COX inhibition limit muscle oxygen uptake at the onset of moderate-intensity exercise in male subjects?
Does reduced blood flow via NOS and COX inhibition limit muscle oxygen uptake at the onset of moderate-intensity exercise in male subjects?
Muscle blood flow and oxygen delivery can be markedly reduced without affecting muscle oxygen uptake in the initial phase of moderate-intensity exercise, indicating blood flow does not limit oxygen uptake at exercise onset.
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Challenges assumption that blood flow limits muscle oxygen uptake at exercise onset; leaves open compensatory mechanisms in health and disease.
Nyberg et al. (2010) studied this question.
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