Why the study?
Does sequential inhibition of NOS and COX reduce leg vasodilation and alter oxygen consumption during prolonged low-intensity exercise in untrained young adults?
Population
13 untrained healthy young adults
Comparison
Sequential pharmacological inhibition of nitric… vs Control values (exercise without inhibitors)
Design
Other
Follow-up
25 minutes
Authors
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No sustained clinical effects on exercise hemodynamics; leaves open redundant vasodilator pathways in untrained adults.
Does sequential inhibition of NOS and COX reduce leg vasodilation and alter oxygen consumption during prolonged low-intensity exercise in untrained young adults?
NOS and COX have a modest, transient role in leg vasodilation during prolonged steady-state exercise in untrained humans, and do not influence muscle oxygen consumption.
Schrage et al. (2010) studied this question.
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