Why the study?
Does dipyridamole combined with aspirin reduce the risk of stroke compared to aspirin alone in patients with cerebrovascular disease?
Population
Patients with cerebrovascular disease from ESPS-2 and 14 previous trials
Comparison
Dipyridamole combined with aspirin vs Aspirin alone
Design
Meta-analysis
Authors
Loading...
Supports dipyridamole-aspirin over aspirin alone for secondary stroke prevention; confirms benefit across 15 trials in meta-analysis.
Does dipyridamole combined with aspirin reduce the risk of stroke compared to aspirin alone in patients with cerebrovascular disease?
Aggregating ESPS-2 with 14 previous trials demonstrates that dipyridamole plus aspirin reduces stroke risk by 23% compared to aspirin alone in patients with cerebrovascular disease.
Wilterdink et al. (1999) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: