Why the study?
Does streptokinase or Arvin improve complete thrombolysis compared to heparin in patients with deep vein thrombosis of the legs?
Population
30 patients with deep vein thrombosis of the legs of less than four days' duration
Comparison
Streptokinase or Arvin under laboratory control vs Heparin under laboratory control
Design
RCT, allocated at random
Authors
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Streptokinase may be prioritized for maximal thrombolysis in acute DVT; confirms RCT superiority over heparin while Arvin minimizes complications.
Does streptokinase or Arvin improve complete thrombolysis compared to heparin in patients with deep vein thrombosis of the legs?
In patients with acute deep vein thrombosis, streptokinase achieves the highest rates of complete anatomical thrombolysis compared to heparin or Arvin, though Arvin is associated with the fewest complications.
Kakkar et al. (1969) studied this question.