Why the study?
Do specific patient characteristics predict noncardiovascular adverse effects in patients receiving amiodarone for arrhythmias?
Population
44 patients receiving amiodarone for supraventricular or ventricular arrhythmias
Comparison
Amiodarone therapy vs Internal comparison between patients who…
Design
Cohort
Follow-up
mean duration of therapy 99.5 +/- 110.8 weeks
Authors
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May warrant closer monitoring in younger patients or those with low LVEF; leaves open prospective validation of these associations.
Do specific patient characteristics predict noncardiovascular adverse effects in patients receiving amiodarone for arrhythmias?
Age less than 60 years and severely depressed left ventricular ejection fraction may be risk factors for amiodarone-induced dermatologic and hepatic adverse effects, respectively.
Tisdale et al. (1995) studied this question.
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