February 1, 2001American Journal of Hypertension
Left ventricular hypertrophy and angiotensin II antagonists
Key result
Angiotensin II antagonists demonstrate significant clinical efficacy in reversing left ventricular hypertrophy in patients with hypertension based on published studies.
Why the study?
Do selective angiotensin II antagonists improve regression of left ventricular hypertrophy in patients with hypertension?
Population
Patients with hypertension and left ventricular hypertrophy
Design
Review
Authors
Discussion
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Member takes
Implication
May support angiotensin II antagonists for LVH regression in hypertension; leaves open need for randomized confirmation.
Structured PICO
Do selective angiotensin II antagonists improve regression of left ventricular hypertrophy in patients with hypertension?
P
Population
Patients with hypertension and left ventricular hypertrophy
I
Intervention
Selective angiotensin II antagonists (e.g., losartan, valsartan, irbesartan, candesartan)
O
Outcome
Regression of left ventricular hypertrophysurrogate
Angiotensin II antagonists demonstrate significant efficacy in reversing left ventricular hypertrophy among hypertensive patients.
Cite This Study
Björn Dahlöf (2001) conducted a review in Left ventricular hypertrophy in patients with hypertension. Angiotensin II antagonists was evaluated on Regression of left ventricular hypertrophy. Angiotensin II antagonists demonstrate significant clinical efficacy in reversing left ventricular hypertrophy in patients with hypertension based on published studies.