Key result
Overall evidence from animal models and meta-analyses supports a major role for ACE inhibitors in reducing left ventricular hypertrophy in patients with hypertension.
Why the study?
Do ACE inhibitors promote regression of left ventricular hypertrophy in patients with hypertension?
Do ACE inhibitors promote regression of left ventricular hypertrophy in patients with hypertension?
ACE inhibitors may have a superior role in promoting the regression of left ventricular hypertrophy in hypertensive patients independently of their blood pressure lowering effect.
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Supports ACE inhibitor preference for LVH regression beyond BP lowering; leaves open need for dedicated RCTs to confirm.
Richards et al. (1994) conducted a review in Hypertension with left ventricular hypertrophy. ACE inhibitors was evaluated. Overall evidence from animal models and meta-analyses supports a major role for ACE inhibitors in reducing left ventricular hypertrophy in patients with hypertension.
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