Why the study?
Are there histological abnormalities in limb and respiratory muscles of patients with chronic heart failure compared to controls?
Are there histological abnormalities in limb and respiratory muscles of patients with chronic heart failure compared to controls?
Histological abnormalities are present in the limb and respiratory muscles of patients with chronic heart failure, particularly those with idiopathic dilated cardiomyopathy, which may contribute to the pathogenesis of dyspnoea.
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Suggests diaphragmatic histology may contribute to dyspnea in idiopathic dilated cardiomyopathy; hypothesis-generating and needs prospective validation.
Lindsay et al. (1996) studied this question.
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