What question did this study set out to answer?

The study aims to investigate the variability of plasma TAFI antigen levels and their relationship with cardiovascular risk factors.

September 1, 2000Arteriosclerosis Thrombosis and Vascular BiologyOpen Access

Thrombin-Activatable Fibrinolysis Inhibitor Antigen Levels and Cardiovascular Risk Factors

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The study aims to investigate the variability of plasma TAFI antigen levels and their relationship with cardiovascular risk factors.
Analyzed plasma TAFI antigen levels in 626 consecutive patients attending a metabolic ward for primary prevention.
Examined associations with cardiovascular risk factors, adjusting for age and sex.
Utilized stepwise multiple linear regression analysis to assess contributory factors.
Interindividual variability of TAFI antigen levels ranged widely, with a 2- to 3-fold increase between the 10th and 90th percentiles.
Age correlated with TAFI levels in women, while men showed positive associations with waist-to-hip ratio and blood pressure.
Overall, cardiovascular risk factors accounted for only 16% and 9.5% of the variance in fibrinogen levels for men and women, respectively.

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Implication

Randomized trial examines TAFI antigen levels and their link to cardiovascular risk factors in patients, suggesting genetic control may be significant.

Cite This Study

Juhan-Vague et al. (2000) studied this question.

synapsesocial.com/papers/6a2128f29ce783ab469d19c5 https://doi.org/10.1161/01.atv.20.9.2156

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Implication

Randomized trial examines TAFI antigen levels and their link to cardiovascular risk factors in patients, suggesting genetic control may be significant.

Thrombin-Activatable Fibrinolysis Inhibitor Antigen Levels and Cardiovascular Risk Factors

Key Points

Discussion

Implication

Cite This Study

Thrombin-Activatable Fibrinolysis Inhibitor Antigen Levels and Cardiovascular Risk Factors

Key Points

Discussion

Implication

Cite This Study

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