Key result
Mean TAFI antigen values were significantly lower in black African men compared to age-matched Caucasian men (87% vs 114%; p<0.0001), though levels remained highly stable within individuals over time.
Population
249 healthy individuals
Design
Cross-sectional
Follow-up
several months
Authors
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Racial differences in TAFI levels should not yet alter practice; leaves open their role in thrombosis risk variation across populations.
Observational (n=249)
Absolute Event Rate: 87% vs 114%
p-value: p=<0.0001
Plasma TAFI antigen levels exhibit wide inter-individual variation but remain stable within individuals over time, with significant differences observed between racial groups.
Chétaille et al. (2000) conducted an observational in Healthy (n=249). Black African race vs. Caucasian race was evaluated on Mean TAFI antigen value (p=<0.0001). Mean TAFI antigen values were significantly lower in black African men compared to age-matched Caucasian men (87% vs 114%; p<0.0001), though levels remained highly stable within individuals over time.
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