Why the study?
Does infusion of specific atrial natriuretic peptides inhibit the release of other atrial natriuretic peptides in healthy human subjects?
Population
30 healthy human subjects
Comparison
Infusion of 100 ng/kg BW.min for 60 min of each… vs Infusion of vehicle only
Design
Other
Follow-up
60 min
Authors
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No immediate change to natriuretic peptide monitoring in practice; leaves open their regulatory dynamics in cardiovascular disease.
Does infusion of specific atrial natriuretic peptides inhibit the release of other atrial natriuretic peptides in healthy human subjects?
Atrial natriuretic peptides exert negative feedback on their own and each other's release in healthy humans.
Vesely et al. (1994) studied this question.
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