Why the study?
How does cardiac denervation affect the utilization of left ventricular residual volume to increase cardiac output during exercise in dogs?
How does cardiac denervation affect the utilization of left ventricular residual volume to increase cardiac output during exercise in dogs?
In a canine model, cardiac denervation shifts the mechanism of increasing cardiac output during exercise from utilizing residual left ventricular volume to increasing ventricular filling.
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May inform post-transplant exercise physiology; extends animal denervation data but should not yet guide practice.
Bruce et al. (1965) studied this question.
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