Key result
Captopril monotherapy reduced mean systolic and diastolic blood pressures by 17 and 11 mm Hg, respectively, with only 4.9% of patients requiring discontinuation due to adverse events.
Why the study?
Does captopril monotherapy reduce blood pressure and improve quality of life in patients with hypertension?
Observational (n=30,515)
Yes
Does captopril monotherapy reduce blood pressure and improve quality of life in patients with hypertension?
Captopril monotherapy is an effective and well-tolerated antihypertensive treatment across diverse patient groups that also improves quality of life.
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Captopril monotherapy was associated with BP reductions and low discontinuations in this cohort; leaves open comparative effectiveness versus other agents.
James A. Schoenberger (1990) conducted an observational in Hypertension (n=30,515). Captopril monotherapy was evaluated on Reduction in mean systolic and diastolic blood pressures. Captopril monotherapy reduced mean systolic and diastolic blood pressures by 17 and 11 mm Hg, respectively, with only 4.9% of patients requiring discontinuation due to adverse events.
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