Why the study?
Emerging research highlights multiple connections between cardiovascular disease and cancer, motivating an examination of reverse cardio-oncology and the heightened risk of cancer in patients with cardiovascular disease.
Does cardiovascular disease increase the risk and progression of cancer?
Does cardiovascular disease increase the risk and progression of cancer?
Highlights the emerging concept of reverse cardio-oncology, suggesting that cardiovascular disease can promote cancer development, necessitating integrated bidirectional cardio-oncology care.
Supports bidirectional cardio-oncology evaluation; leaves open causal confirmation in prospective studies.
Having established the significance of cardiovascular side-effects of anti-neoplastic drugs, present day cardio-oncology has forayed into newer territories buoyed by research into the multiple connections that exist between cardiovascular disease and cancer. An emerging concept of reverse cardio-oncology focuses on the heightened risk of cancer in patients with cardiovascular disease. Common mechanistics of cancer and heart failure (HF) like chronic inflammation and clonal haematopoesis as well as common predisposing factors like obesity and diabetes underline the relation between both cardiovascular disease and various cancers.This review discusses the potential magnitude of the problem, the underlying pathophysiological mechanisms and classification of this novel subject.
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Satpathy et al. (2023) conducted a review in Cardiovascular disease and cancer. Cardiovascular disease and shared risk factors was evaluated.
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