Why the study?
Does the ACE-DD genotype alter exercise-induced muscle metabolism compared to ACE-ID/II genotypes in untrained men?
Population
53 not-specifically trained Caucasian men
Comparison
ACE-DD genotype vs ACE-ID and ACE-II genotypes
Design
Cross-sectional
Follow-up
Immediate post-exercise
Authors
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ACE-DD may link to altered post-exercise glucose handling; hypothesis-generating and requires prospective confirmation before clinical consideration.
Does the ACE-DD genotype alter exercise-induced muscle metabolism compared to ACE-ID/II genotypes in untrained men?
The ACE-DD genotype is associated with altered glucose import and oxidation during exhaustive exercise, potentially predisposing individuals to a pre-diabetic state.
Vaughan et al. (2016) studied this question.
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