Reference Values for SphygmoCor Measurements in South Africans of African Ancestry
Key result
SphygmoCor measurements in healthy South Africans of African descent established preliminary diagnostic thresholds for increased arterial stiffness at age 30, including a pulse wave velocity of 8.0 m/sec.
Population
185 healthy subjects of African descent living in South Africa, mean age 33.5 years, 77 men and 108 women.
Design
Cross-sectional
Authors
Discussion
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Implication
Provides preliminary ethnicity-specific arterial stiffness thresholds in young South Africans; leaves open prospective validation before clinical use.
Study Design
Type
Cross-Sectional (n=185)
Structured PICO
P
Population
185 healthy South African adults of African descent, free of hypertension, diabetes, and cardiovascular disease, assessed to establish reference values for arterial stiffness.
E
Exposure
Applanation tonometry using SphygmoCor software to measure arterial stiffness indexes (peripheral and central pulse pressures, augmentation indexes, and aortic pulse wave velocity)
O
Outcome
Distributional characteristics and 95th prediction bands of peripheral and central pulse pressures, augmentation indexes, and aortic pulse wave velocitysurrogate
The study establishes preliminary age-adjusted diagnostic thresholds for arterial stiffness indexes in healthy young adult South Africans of African descent.
Limitations
- Pending validation in prospective outcome-based studies
Cite This Study
SHIBURI et al. (2006) conducted a cross-sectional in Healthy subjects (n=185). SphygmoCor measurements was evaluated on 95th prediction bands for arterial stiffness indexes at age 30 years. SphygmoCor measurements in healthy South Africans of African descent established preliminary diagnostic thresholds for increased arterial stiffness at age 30, including a pulse wave velocity of 8.0 m/sec.