A polyaniline microtube platform for direct electron transfer of glucose oxidase and biosensing applications

in PBS solution (0.1 M, pH = 5.5) on the PANI microtubes instead of a bare glass carbon electrode (GCE). The amperometric response of the GOx/PANI microtube modified electrode was linearly proportional to the concentration of glucose in the range of 4.0 μM to 0.80 mM. The glucose detection limit was 0.8 μM at a signal-to-noise ratio of 3, which was better than those reported for the GOx/PANI film (1 mM) and GOx/PANI nanowire (50 μM). The advantages might be attributed to the PANI microtubes' large geometric surface for carrying enzyme (GOx) and efficient electrocatalytic activity to facilitate the direct electron transfer of GOx, as well as an efficient GOx biocatalyst reaction on the microtube surface. A promising application of PANI microtube-based biosensors was offered.