Key result
Plasma BNP levels were significantly higher in patients with ARVD (61.4 pg/mL) compared to RVOT patients (8.3 pg/mL) and control subjects (9.3 pg/mL; P<0.0001).
Why the study?
Does plasma BNP level differentiate patients with Arrhythmogenic Right Ventricular Dysplasia from those with idiopathic RV outflow tract tachycardia and healthy controls?
Observational (n=149)
Does plasma BNP level differentiate patients with Arrhythmogenic Right Ventricular Dysplasia from those with idiopathic RV outflow tract tachycardia and healthy controls?
Absolute Event Rate: 61.4% vs 9.3%
p-value: p=<0.0001
Plasma BNP levels are significantly elevated in patients with ARVD compared to those with RVOT or healthy controls, and correlate with the severity of RV dysfunction.
No takes yet. Share an insight, caveat, or question.
May support BNP testing in suspected ARVD; leaves open diagnostic utility versus RVOT tachycardia pending prospective studies.
Matsuo et al. (1998) conducted an observational in Arrhythmogenic right ventricular dysplasia (ARVD) (n=149). Arrhythmogenic right ventricular dysplasia (ARVD) vs. RVOT patients and control subjects was evaluated on Plasma BNP levels (p=<0.0001). Plasma BNP levels were significantly higher in patients with ARVD (61.4 pg/mL) compared to RVOT patients (8.3 pg/mL) and control subjects (9.3 pg/mL; P<0.0001).
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