Key result
Captopril effectively controlled blood pressure in patients with renal artery stenosis and resistant hypertension, inducing significant falls in arterial pressure, angiotensin II, and aldosterone.
Why the study?
Does captopril improve blood pressure and hormonal profiles in patients with hypertension due to renal artery stenosis or resistant hypertension?
Population
Hypertensive patients with renal artery stenosis and patients resistant to other therapy
Design
Case_series
Follow-up
long-term
Authors
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May support captopril in resistant renovascular hypertension; leaves open need for randomized confirmation.
Does captopril improve blood pressure and hormonal profiles in patients with hypertension due to renal artery stenosis or resistant hypertension?
Captopril effectively controls blood pressure in patients with renal artery stenosis and resistant hypertension by reducing angiotensin II and aldosterone levels.
Atkinson et al. (1979) studied Hypertension with renal artery stenosis and intractable hypertension. Captopril was evaluated on Blood pressure control and changes in circulating concentrations of renin, angiotensins I and II, and aldosterone. Captopril effectively controlled blood pressure in patients with renal artery stenosis and resistant hypertension, inducing significant falls in arterial pressure, angiotensin II, and aldosterone.
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