Key result
Antihypertensive drug therapy resulted in a significant reduction in coronary heart disease among over 37,000 treated patients.
Why the study?
Does antihypertensive drug therapy reduce coronary heart disease and other cardiovascular events in patients with hypertension?
Population
Over 37,000 patients treated for hypertension across 14 randomized trials
Comparison
Antihypertensive drug therapy vs Placebo or control
Design
Review
Authors
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Supports BP control to reduce CHD; leaves open optimal regimens in modern populations.
Does antihypertensive drug therapy reduce coronary heart disease and other cardiovascular events in patients with hypertension?
This overview highlights that antihypertensive therapy significantly reduces coronary heart disease, reinforcing the broad cardiovascular benefits of blood pressure control.
Marvin Moser (1991) conducted a review in hypertension (n=37,000). Antihypertensive drug therapy vs. placebo or control was evaluated on coronary heart disease (CHD). Antihypertensive drug therapy resulted in a significant reduction in coronary heart disease among over 37,000 treated patients.
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