Why the study?
Does 60 degrees upright tilt elicit abnormal neurohumoral and hemodynamic responses in patients with congestive heart failure?
Population
n=35 patients with varying degrees of congestive heart failure
Comparison
60 degrees upright tilt vs Baseline resting state and normal subjects
Design
Cross-sectional
Authors
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Blunted neurohumoral responses to tilt in severe CHF suggest baroreceptor impairment; hypothesis-generating for autonomic mechanisms and requires prospective validation.
Does 60 degrees upright tilt elicit abnormal neurohumoral and hemodynamic responses in patients with congestive heart failure?
Patients with severe congestive heart failure exhibit blunted neurohumoral and hemodynamic responses to orthostatic tilt, suggesting impaired mechanoreceptor or baroreceptor function.
Levine et al. (1983) studied this question.
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