Key result
Cigarette smoking increased 25-year all-cause mortality in men with low serum cholesterol, with death rates up to 428.0 per 1,000 and absolute excess rates up to 225.7 per 1,000.
Why the study?
Does cigarette smoking increase 25-year mortality in middle-aged men with low baseline serum cholesterol?
Population
8,816 middle-aged men screened between 1967 and 1973 by the Chicago Heart Association Detection Project in…
Comparison
Cigarette smoking (current smokers at baseline) vs Men who never smoked
Design
Cohort
Follow-up
25 years
Authors
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Supports smoking cessation in low-cholesterol men; extends observational evidence on independent risks but leaves causality open.
Cohort (n=8,816)
Does cigarette smoking increase 25-year mortality in middle-aged men with low baseline serum cholesterol?
Cigarette smoking remains a strong independent risk factor for coronary, cardiovascular, and all-cause mortality even in men with low baseline serum cholesterol levels.
Lucila Blanco-Cedres (2002) conducted a cohort in Low baseline serum cholesterol (n=8,816). Cigarette smoking vs. Never smoked was evaluated on 25-year coronary, cardiovascular, and all-cause mortality. Cigarette smoking increased 25-year all-cause mortality in men with low serum cholesterol, with death rates up to 428.0 per 1,000 and absolute excess rates up to 225.7 per 1,000.
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