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June 16, 2021JACC. Cardiovascular imagingOpen Access

AI-Assisted Echocardiographic Prescreening of Heart Failure With Preserved Ejection Fraction on the Basis of Intrabeat Dynamics

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Why the study?

Although diagnostic criteria for HFpEF have been established, rapid and accurate assessment of HFpEF using echocardiography remains challenging and highly desirable.

Does an AI-assisted echocardiographic prescreening tool based on intrabeat dynamics accurately detect HFpEF?

Population

1,041 HFpEF patients, 1,263 asymptomatic individuals, plus 150 COPD and 315 HFpEF external validation patients

Comparison

AI-based echocardiographic intrabeat dynamic assessment vs asymptomatic individuals and symptomatic COPD controls

Design

Model development and external validation study

Authors

YCYu-An ChiouCHChung‐Lieh HungSLSHIEN‐FONG LIN

Discussion

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Overview

Should not yet change HFpEF diagnostic practice; leaves open external validation and prospective trials.

Structured PICO

Does an AI-assisted echocardiographic prescreening tool based on intrabeat dynamics accurately detect HFpEF?

P
Population
1,041 patients with HFpEF and 1,263 asymptomatic individuals (internal dataset), and an external testing dataset of 150 patients with symptomatic chronic obstructive pulmonary disease and 315 patients with HFpEF
I
Intervention
AI-assisted echocardiographic prescreening tool based on intrabeat dynamic changes in the left ventricle and left atrium from 4-chamber view images
C
Comparator
Clinical diagnosis (asymptomatic individuals or patients with COPD)
O
Outcome
Diagnostic accuracy, sensitivity, specificity, and area under the receiver-operating characteristic curve (AUC) for detecting HFpEFsurrogate

An AI model analyzing intrabeat dynamics from 4-chamber echocardiographic views provides a rapid and accurate prescreening method for detecting HFpEF.

Cite This Study

Chiou et al. (2021) studied this question.

synapsesocial.com/papers/6a35da3fa4e90ae4d3ef5011https://doi.org/10.1016/j.jcmg.2021.05.005
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Heart failure with preserved ejection fraction in Asia2018 · 164 citations
  2. 2Trends in Patients Hospitalized With Heart Failure and Preserved Left Ventricular Ejection Fraction2012 · 780 citations
  3. 3Phenomapping for Novel Classification of Heart Failure With Preserved Ejection Fraction2014 · 1,157 citations
  4. 42016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure2016 · 11,598 citations
  5. 5Spironolactone for Heart Failure with Preserved Ejection Fraction2014 · 2,810 citations