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September 1, 2026Structural HeartOpen Access

Association of a Novel Echocardiographic AI Model with Invasive Hemodynamics to Automate Detection of Heart Failure with Preserved Ejection Fraction (HFpEF)

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Key result

Novel echocardiographic AI model for detecting HFpEF requires validation against invasive hemodynamics.

Why the study?

While AI models applied to echocardiograms show promise for HFpEF discrimination, their correlation with gold-standard invasive hemodynamics has yet to be evaluated.

Does a novel echocardiographic AI model correlate with invasive hemodynamics for the detection of HFpEF?

Comparison

Echocardiographic AI model vs gold-standard invasive hemodynamics

Authors

NHNadira HamidMinneapolis Heart Institute FoundationAAAshley P. AkermanBoston University
Marat Fudim
Marat FudimHeart Failure / Cardiomyopathy

Discussion

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Member takes

Overview

Cannot yet guide HFpEF diagnosis; leaves open correlation with invasive hemodynamics pending quantitative validation.

Key Points

  • Assess the association of a novel artificial intelligence echocardiographic model with gold-standard invasive hemodynamics to automate the detection of heart failure with preserved ejection fraction.
  • Applied an artificial intelligence model to transthoracic echocardiograms to identify heart failure with preserved ejection fraction.
  • Evaluated model diagnostic performance relative to standard clinical risk scores and gold-standard invasive hemodynamic assessments.
  • Artificial intelligence applied to transthoracic echocardiography showed superior discriminative capability for heart failure with preserved ejection fraction compared to conventional clinical scores.
  • Investigation provides the foundation for correlating noninvasive imaging algorithms with invasive hemodynamic measurements.

Study Design

Type

Observational

Structured PICO

Does a novel echocardiographic AI model correlate with invasive hemodynamics for the detection of HFpEF?

E
Exposure
Novel Echocardiographic AI Model applied to transthoracic echocardiograms (TTE)
C
Comparator
Invasive hemodynamic assessment
O
Outcome
Correlation with gold-standard invasive hemodynamics for detection of HFpEFsurrogate

This text outlines the rationale for evaluating the correlation between an echocardiographic AI model and invasive hemodynamics for detecting HFpEF, but provides no results.

Cite This Study

Hamid et al. (2026) conducted an observational in Heart Failure with Preserved Ejection Fraction (HFpEF). Echocardiographic AI Model vs. Invasive hemodynamics was evaluated on Correlation with invasive hemodynamics. A novel echocardiographic AI model for detecting HFpEF requires evaluation against gold-standard invasive hemodynamics, as no quantitative results are reported in the abstract.

synapsesocial.com/papers/6aa910f83319b89d6829a273https://doi.org/10.1016/j.shj.2026.101120
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Automated Echocardiographic Detection of Heart Failure With Preserved Ejection Fraction Using Artificial Intelligence2023 · 108 citations
  2. 2Invasive haemodynamic validation of an artificial intelligence echocardiographic tool for detecting heart failure with preserved ejection fraction2026
  3. 3External validation of artificial intelligence for detection of heart failure with preserved ejection fraction2025 · 32 citations
  4. 4Artificial Intelligence-Enabled Electrocardiogram Model for Predicting Heart Failure with Preserved Ejection Fraction– A Single-Center Study2025 · 12 citations
  5. 5AI-Assisted Echocardiographic Prescreening of Heart Failure With Preserved Ejection Fraction on the Basis of Intrabeat Dynamics2021 · 66 citations