Key result
Patients aged ≥60 years had a lower ejection fraction (42% vs 53%, P<.01) and greater end-systolic volume index (75 vs 44 mL/m2, P<.01) after myocardial infarction compared to younger patients.
Why the study?
Does age-related vascular stiffness affect left ventricular remodeling and size after myocardial infarction?
Observational (n=49)
Does age-related vascular stiffness affect left ventricular remodeling and size after myocardial infarction?
Absolute Event Rate: 42% vs 53%
p-value: p=<.01
Older patients exhibit increased left ventricular size and lower ejection fraction after myocardial infarction, which is independently predicted by infarct size and reduced aortic distensibility.
No takes yet. Share an insight, caveat, or question.
May link age-related stiffness to worse post-MI remodeling; hypothesis-generating, should not yet change practice.
Hirsch et al. (2007) conducted an observational in Myocardial infarction (n=49). Age ≥60 years vs. Younger patients was evaluated on Ejection fraction (p=<.01). Patients aged ≥60 years had a lower ejection fraction (42% vs 53%, P<.01) and greater end-systolic volume index (75 vs 44 mL/m2, P<.01) after myocardial infarction compared to younger patients.
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