Key result
Aortic propagation velocity strongly correlates with aging and pulse wave velocity on transthoracic echocardiography.
Why the study?
Does color M-mode echocardiography-derived propagation velocity of the descending aorta correlate with established measures of arterial stiffness and subclinical atherosclerosis in healthy adults?
Cross-Sectional (n=130)
Single-blind (assessor)
No
Does color M-mode echocardiography-derived propagation velocity of the descending aorta correlate with established measures of arterial stiffness and subclinical atherosclerosis in healthy adults?
Effect estimate: r = -0.902
p-value: p=<0.001
Color M-mode echocardiography-derived propagation velocity of the descending aorta is a simple, noninvasive parameter that correlates strongly with established measures of arterial stiffness and subclinical atherosclerosis in healthy adults.
AVP may offer a simple echocardiographic stiffness marker in healthy adults; leaves open prospective validation for risk stratification or outcomes.
Background: Arterial stiffness (AS) can be determined by some noninvasive tests such as pulse wave velocity (PWV). Atherosclerosis is also detectable by some ultrasonographic techniques such as color M-mode-derived propagation velocity measured along the origin of the descending aorta (AVP). Aim: The aim of the study was to find out a possible relationship between atherosclerosis and AVP and whether AVP can be used as a parameter of AS. Materials and methods: The study group was composed of 134 people from routine screening examination who were ≥40 years old, completely healthy, and without any known disease and use of any drug. PWV has been determined to show aortic stiffness, and carotid artery intima–media thickness (CIMT) was measured for subclinical atherosclerosis. AVP values were obtained from all participants, and correlations were calculated between these parameters and age. Results: AVP decreased ( r =−0.902, P <0.001) and PWV increased ( r =0.854, P <0.001) significantly with increasing age. CIMT also increased with aging ( r =0.518, P <0.001). There were significant correlations between AVP and PWV ( r =−0.832, P <0.001) and AVP and CIMT ( r =−0.345, P <0.001). Conclusion: Transthoracic echocardiographic determination of AVP can be used as a simple measurement of AS and correlates well with PWV, age, and CIMT in healthy people.
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Yaman et al. (2017) conducted a cross-sectional in Healthy adults (n=130). Increasing age was evaluated on Correlation between aortic propagation velocity (AVP) and age (r = -0.902, p=<0.001). Aortic propagation velocity (AVP) measured by transthoracic echocardiography decreased significantly with increasing age (r = -0.902) and strongly correlated with pulse wave velocity (r = -0.832).
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