Key result
Inflammatory bowel disease was associated with significantly increased aortic stiffness, demonstrated by reduced aortic strain (7.38% vs 15.1%) and distensibility, which correlated with subclinical left ventricular dysfunction.
Why the study?
Is inflammatory bowel disease associated with increased aortic stiffness and left ventricular dysfunction in patients without traditional cardiovascular risk factors?
Case-Control (n=122)
Single-blind
No
Is inflammatory bowel disease associated with increased aortic stiffness and left ventricular dysfunction in patients without traditional cardiovascular risk factors?
Absolute Event Rate: 7.38% vs 15.1%
p-value: p=<0.001
Patients with inflammatory bowel disease exhibit increased aortic stiffness and subclinical left ventricular dysfunction independent of traditional cardiovascular risk factors, suggesting a role for chronic inflammation in early cardiovascular risk.
Aortic stiffness differences in IBD may signal higher CV risk; leaves open causal links to LV dysfunction and need for prospective validation.
No takes yet. Share an insight, caveat, or question.
Aslan et al. (2016) conducted a case-control in Inflammatory bowel disease (n=122). Inflammatory bowel disease vs. Healthy controls was evaluated on Aortic strain (p=<0.001). Inflammatory bowel disease was associated with significantly increased aortic stiffness, demonstrated by reduced aortic strain (7.38% vs 15.1%) and distensibility, which correlated with subclinical left ventricular dysfunction.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: