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June 29, 2026Analytical Chemistry

Multiplexed Sepsis Immunosorbent Assay Based on Flower-like CoFe 2 O 4 /MoS 2 with Dual Substrate Affinity

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Authors

TLTai-Cheng LuFujian Medical UniversityQQQing-Zhen QiuFujian Medical UniversityWCWen-Xin ChenFujian Medical University

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Overview

Randomized trial evaluates a novel assay for detecting sepsis biomarkers, indicating improved diagnosis in clinical settings.

Key Points

  • The aim is to develop a multiplexed immunosorbent assay for the improved diagnosis of sepsis using biomarker detection.
  • Developed a novel nanozyme-linked immunosorbent assay kit for detecting three sepsis biomarkers.
  • Utilized a flower-like CoFe2O4/MoS2 nanosheet with dual substrate affinity as the nanozyme label.
  • Conducted clinical validation with plasma samples from sepsis patients.
  • Demonstrated strong concordance with enzyme-linked immunosorbent assay tests, confirming improved diagnostic reliability.
  • Achieved robust sensitivity and specificity for the multiplexed detection of C-reactive protein, serum amyloid A, and D-dimer.

Cite This Study

Lu et al. (2026) studied this question.

synapsesocial.com/papers/6a420ab2f91bb43ea9191e90https://doi.org/10.1021/acs.analchem.5c07042
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Also Consider

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