June 1, 1995American Journal of Hypertension
Ethnic differences in hemodynamic responses to stress in hypertensive men and women*
Key result
Black subjects exhibited greater vascular tone mediating pressor responses to stress compared to white subjects, despite similar overall blood pressure increases.
Why the study?
Do hemodynamic responses to laboratory stressors differ by ethnicity and gender in mildly hypertensive adults?
Population
63 mildly hypertensive black and white men and women, matched for age, body mass index, and casual blood…
Comparison
Three laboratory stressors: mental arithmetic… vs Comparison between ethnic groups and genders
Design
Cross-sectional
Authors
Discussion
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Implication
May inform ethnicity-specific vascular assessment in hypertension; hypothesis-generating and requires prospective validation.
Key Points
- This research aims to compare the hemodynamic responses to stress among mildly hypertensive black and white men and women.
- Compared responses in 63 mildly hypertensive black and white individuals, matched for age and body mass index.
- Examined responses to three stressors: mental arithmetic, public speaking, and cold pressor test.
- Analyzed changes in blood pressure and heart rate across gender and ethnic groups.
- Blood pressure increases during stress were similar for both ethnic groups.
- Greater vascular tone in black subjects versus white subjects was observed across stressors.
- Women showed increased heart rates but smaller vascular contributions to blood pressure increases compared to men.
Study Design
Type
Cross-Sectional (n=63)
Structured PICO
Do hemodynamic responses to laboratory stressors differ by ethnicity and gender in mildly hypertensive adults?
P
Population
63 mildly hypertensive black and white men and women evaluated for hemodynamic responses to laboratory stressors.
E
Exposure
Three laboratory stressors: mental arithmetic task, simulated public speaking task, and forehead cold pressor test
C
Comparator
Comparison between ethnic groups (black vs. white) and genders (men vs. women)
O
Outcome
Hemodynamic response patterns (blood pressure increases, vascular tone, systemic vascular resistance, heart rate)surrogate
Black subjects exhibit greater vascular tone mediating pressor responses to stress compared to white subjects, suggesting different pathophysiological mechanisms in hypertension based on ethnicity.
Cite This Study
Sherwood et al. (1995) conducted a cross-sectional in Mild hypertension (n=63). Black ethnicity vs. White ethnicity was evaluated on Hemodynamic response patterns to laboratory stressors. Black subjects exhibited greater vascular tone mediating pressor responses to stress compared to white subjects, despite similar overall blood pressure increases.