Key result
Fluctuations in anti-Ro/SS-A and anti-La/SS-B autoantibody levels were unrelated to disease activity or the occurrence of congenital heart block over an 80-month period.
Why the study?
Can frequent measurement of anti-Ro/SS-A and anti-La/SS-B levels predict the occurrence of congenital heart block in a patient with systemic lupus erythematosus?
Population
1 patient with systemic lupus erythematosus
Design
Case_report
Follow-up
80 months
Authors
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Serial anti-Ro/La monitoring may not inform congenital heart block risk; leaves open need for prospective validation of other predictors.
Case Report (n=1)
Can frequent measurement of anti-Ro/SS-A and anti-La/SS-B levels predict the occurrence of congenital heart block in a patient with systemic lupus erythematosus?
Frequent measurement of anti-Ro/SS-A and anti-La/SS-B levels cannot predict the occurrence of congenital heart block in patients with systemic lupus erythematosus.
Derksen et al. (1992) conducted a case report in Systemic lupus erythematosus (n=1). Anti-Ro/SS-A and anti-La/SS-B autoantibody levels was evaluated on Occurrence of congenital heart block and disease activity. Fluctuations in anti-Ro/SS-A and anti-La/SS-B autoantibody levels were unrelated to disease activity or the occurrence of congenital heart block over an 80-month period.
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