What question did this study set out to answer?

To evaluate the performance of the Sidekick POC progesterone test for equine reproductive management compared to traditional methods.

Evaluation of the Sidekick point-of-care progesterone lateral-flow assay for use in equine reproductive management

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Randomized trial evaluates clinical accuracy of a new progesterone test in mares, suggesting on-the-spot decisions improve care.

To evaluate the performance of the Sidekick POC progesterone test for equine reproductive management compared to traditional methods.
Evaluated performance using mare plasma with 0-8 ng/mL progesterone.
Compared results from Sidekick test with RIA and CLIA on 19 serum samples.
Assessed agreement using regression analyses and concordance measures.
LFA recovery rate was 90-102% across 4-8 ng/mL with excellent repeatability (CV 4-15%).
Near-perfect agreement with reference standards in spiked samples (κ = 0.94); substantial agreement in clinical samples (κ = 0.77 RIA, κ = 0.79 CLIA).
No cross-reactivity detected with altrenogest at pharmacologic concentrations.

McDowell et al. (2026) studied this question.

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