Key result
Intra-arterial infusion of noradrenaline or acetylcholine increased the spectral power of the low-frequency systolic blood pressure peak and shifted its central frequency from 0.10 Hz to 0.06 Hz.
Population
Small mesenteric arteries of spontaneously hypertensive and Wistar-Kyoto rats, small omental arteries of…
Comparison
Intra-arterial infusion of noradrenaline or… vs Baseline (before infusion) in Study 2.
Design
Other
Authors
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Spontaneous CVA may confound spectral BP analysis of sympathetic activity; leaves open clinical relevance in hypertension.
Spontaneous cyclic vasomotor activity, mediated by a potassium channel, may contribute to blood pressure variability independently of autonomic nervous system activity.
Rizzoni et al. (1995) studied Mild-to-moderate hypertension (n=18). Intra-arterial infusion of noradrenaline or acetylcholine vs. Baseline (before infusion) was evaluated on Absolute and normalized spectral power of the low-frequency systolic blood pressure peak and its central frequency. Intra-arterial infusion of noradrenaline or acetylcholine increased the spectral power of the low-frequency systolic blood pressure peak and shifted its central frequency from 0.10 Hz to 0.06 Hz.
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