Key result
The PEP/LVET ratio was significantly decreased in the optimized CRT setting compared with RV-only pacing (0.62 vs 0.75, p<0.05), and ICG measurements positively correlated with echocardiography.
Why the study?
Does impedance cardiography correlate with echocardiography for measuring PEP/LVET to optimize cardiac resynchronization therapy in newly CRT implanted patients?
Population
Newly cardiac resynchronization therapy (CRT) implanted patients
Comparison
Impedance cardiography for measuring… vs Echocardiography for measuring PEP/LVET
Design
Cross-sectional
Authors
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ICG PEP/LVET may support CRT optimization in select cases; leaves open need for prospective validation before wider use.
Observational
Does impedance cardiography correlate with echocardiography for measuring PEP/LVET to optimize cardiac resynchronization therapy in newly CRT implanted patients?
Absolute Event Rate: 0.62% vs 0.75%
p-value: p=<0.05
Impedance cardiography correlates positively with echocardiography for measuring PEP/LVET and may be a useful alternative tool for optimizing cardiac resynchronization therapy.
Noda et al. (2016) conducted an observational in Newly implanted cardiac resynchronization therapy (CRT). Optimized CRT setting vs. Right ventricle (RV)-only pacing was evaluated on Pre-ejection period (PEP) to left ventricular ejection time (LVET) ratio (p=<0.05). The PEP/LVET ratio was significantly decreased in the optimized CRT setting compared with RV-only pacing (0.62 vs 0.75, p<0.05), and ICG measurements positively correlated with echocardiography.
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