Why the study?
Are sex hormones and hemostatic risk factors altered in men with hypertension compared to healthy controls?
Population
Men with hypertension and healthy control subjects
Design
Case-control
Authors
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Altered sex hormones may link to hemostatic changes in hypertension; extends the linkage hypothesis but leaves clinical implications open pending trials.
Are sex hormones and hemostatic risk factors altered in men with hypertension compared to healthy controls?
Men with hypertension exhibit decreased testosterone and increased prothrombotic factors (factor VII and PAI-1), suggesting a hormonal link to coronary heart disease risk.
Phillips et al. (1993) studied this question.
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