Key result
In patients with untreated essential hypertension, carotid vascular mass significantly increased with age (r=0.48, p<0.001), indicating progressive vascular remodeling.
Why the study?
Does untreated essential hypertension increase age-related carotid artery remodeling compared to normotensive subjects?
Population
239 subjects, including 163 patients with untreated essential hypertension and 76 normotensive subjects.
Design
Cross-sectional
Authors
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May accelerate age-related carotid remodeling in untreated hypertension after 50; leaves open causal impact on events and need for intervention.
Cross-Sectional (n=239)
No
Does untreated essential hypertension increase age-related carotid artery remodeling compared to normotensive subjects?
Effect estimate: r=0.48
p-value: p=<0.001
Sasaki et al. (2002) conducted a cross-sectional in Untreated essential hypertension (n=239). Untreated essential hypertension and increasing age vs. Normotensive subjects was evaluated on Correlation between age and carotid vascular mass (VM) (r=0.48, p=<0.001). In patients with untreated essential hypertension, carotid vascular mass significantly increased with age (r=0.48, p<0.001), indicating progressive vascular remodeling.