Key result
Hypertension was associated with increased carotid IMT and diameter (P<0.001), and antihypertensive therapy altered the diameter-IMT relationship compared to untreated and normotensive groups.
Why the study?
Does hypertension and its treatment influence early large artery remodeling (carotid IMT and diameter) compared to normotensive subjects?
Cross-Sectional (n=1,249)
Does hypertension and its treatment influence early large artery remodeling (carotid IMT and diameter) compared to normotensive subjects?
p-value: p=<0.001
Antihypertensive therapy alters the sensitivity of carotid artery enlargement in response to increased wall thickness, whereas untreated hypertension does not change this relationship compared to normotension.
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Treated hypertension may alter carotid diameter-IMT coupling versus untreated disease; leaves open whether therapy modifies large-artery adaptation.
Chironi et al. (2003) conducted a cross-sectional in Hypertension (n=1,249). Hypertension vs. Normotensive subjects was evaluated on Carotid intima-media thickness (IMT) and diameter (p=<0.001). Hypertension was associated with increased carotid IMT and diameter (P<0.001), and antihypertensive therapy altered the diameter-IMT relationship compared to untreated and normotensive groups.
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