Key result
Rotavirus strain diversity is extensive, with at least 42 P-G combinations identified, suggesting that rotavirus vaccines must provide good heterotypic protection to be optimally effective.
Design
Review
Authors
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Rotavirus strain diversity supports heterotypic vaccine protection needs; leaves optimal global coverage open for prospective trials.
The enormous diversity of human rotaviruses suggests that rotavirus vaccines must provide good heterotypic protection to be optimally effective.
Gentsch et al. (2005) conducted a review in Rotavirus infection. Rotavirus vaccines was evaluated. Rotavirus strain diversity is extensive, with at least 42 P-G combinations identified, suggesting that rotavirus vaccines must provide good heterotypic protection to be optimally effective.
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