Key result
Nifedipine completely ceased attacks in a patient with Prinzmetal's variant angina complicated by recurrent syncopal episodes that were resistant to standard therapy.
Why the study?
Does nifedipine prevent attacks in a patient with refractory Prinzmetal's variant angina?
Case Report (n=1)
No
Does nifedipine prevent attacks in a patient with refractory Prinzmetal's variant angina?
Nifedipine was highly effective in completely stopping refractory attacks of Prinzmetal's variant angina complicated by ventricular arrhythmias in a single patient.
May support nifedipine in refractory Prinzmetal angina; leaves open confirmation in controlled trials.
Nifedipine is a non-nitrate vasodilator which has proved effective, in oral form, in Europe, Japan, and the USA for treatment of Prinzmetal Angina. The drug has not been used before in Australia. We report a patient with Prinzmetal's variant angina, complicated by recurrent syncopal episodes due to ventricular arrhythmias. The attacks were resistant to standard therapy except sublingual nitroglycerin but ceased completely during treatment with nifedipine.
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Campbell et al. (1979) conducted a case report in Prinzmetal's variant angina (n=1). Nifedipine vs. Standard therapy was evaluated on Angina attacks and syncopal episodes. Nifedipine completely ceased attacks in a patient with Prinzmetal's variant angina complicated by recurrent syncopal episodes that were resistant to standard therapy.
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