December 12, 2015Journal of Clinical HypertensionOpen Access

Higher cardiorespiratory fitness was independently associated with a slower progression of age-related arterial stiffening over 2 years among 470 healthy adults.

Q: What is the clinical evidence from this study?

Study design: Editorial. Population: Healthy adults (n=470). Intervention: Higher cardiorespiratory fitness vs. Low cardiorespiratory fitness. Primary outcome: Progression of age-related arterial stiffening (2-year changes in brachial-ankle pulse wave velocity).

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Key result

Higher cardiorespiratory fitness was independently associated with a slower progression of age-related arterial stiffening over 2 years among 470 healthy adults.

Authors

MDMichael Doumas CBChrysoula Boutari VAVasilios G. Athyros

Discussion

Member takes

Overview

Arterial stiffness measurement may refine CV risk stratification beyond traditional factors; extends meta-analytic support for its prognostic role in hypertension management.

PICO

Population

470 healthy Japanese adults aged 20 to 69 years, free of established cardiovascular disease or risk factors, followed for 2 years.

Exposure / Comparator

Higher cardiorespiratory fitness vs Low cardiorespiratory fitness

Primary Outcome

Progression of age-related arterial stiffening (2-year changes in brachial-ankle pulse wave velocity)

Limitations

Lack of cardiorespiratory fitness assessment at the end of the follow-up period.
Leisure-time physical activity evaluation during the study was not recorded.
Study participants were young and healthy, limiting the generalization of findings to other patient populations.
Two different methods to analyze oxygen consumption and carbon dioxide production were used.
Potential confounding by significant changes in arterial stiffness that occur during the menstrual cycle.

Cite This Study

Doumas et al. (2015) conducted an editorial in Healthy adults (n=470). Higher cardiorespiratory fitness vs. Low cardiorespiratory fitness was evaluated on Progression of age-related arterial stiffening (2-year changes in brachial-ankle pulse wave velocity). Higher cardiorespiratory fitness was independently associated with a slower progression of age-related arterial stiffening over 2 years among 470 healthy adults.

synapsesocial.com/papers/6a650944f28a614c2d895367 https://doi.org/10.1111/jch.12752

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December 12, 2015Journal of Clinical HypertensionOpen Access

Higher cardiorespiratory fitness was independently associated with a slower progression of age-related arterial stiffening over 2 years among 470 healthy adults.

View Full Paper

Ask AI

Bookmark

Key result

Higher cardiorespiratory fitness was independently associated with a slower progression of age-related arterial stiffening over 2 years among 470 healthy adults.

Authors

MDMichael Doumas CBChrysoula Boutari VAVasilios G. Athyros

Discussion

Member takes

Overview

Arterial stiffness measurement may refine CV risk stratification beyond traditional factors; extends meta-analytic support for its prognostic role in hypertension management.

PICO

Population

470 healthy Japanese adults aged 20 to 69 years, free of established cardiovascular disease or risk factors, followed for 2 years.

Exposure / Comparator

Higher cardiorespiratory fitness vs Low cardiorespiratory fitness

Primary Outcome

Progression of age-related arterial stiffening (2-year changes in brachial-ankle pulse wave velocity)

Limitations

Lack of cardiorespiratory fitness assessment at the end of the follow-up period.
Leisure-time physical activity evaluation during the study was not recorded.
Study participants were young and healthy, limiting the generalization of findings to other patient populations.
Two different methods to analyze oxygen consumption and carbon dioxide production were used.
Potential confounding by significant changes in arterial stiffness that occur during the menstrual cycle.

Cite This Study

synapsesocial.com/papers/6a650944f28a614c2d895367 https://doi.org/10.1111/jch.12752

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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