The Relationship Between Cardiorespiratory Fitness and Arterial Stiffness in Middle-Aged Men with Abdominal Obesity

BACKGROUND: Abdominal obesity increases rapidly after middle age in Korean men, and there is an associated trend toward increasing levels of cardiovascular disease (CVD). The purpose of this study was to examine the effect of cardiorespiratory fitness (CRF) on arterial stiffness in men with abdominal obesity. METHODS: A total of 387 middle-aged men (ages 42-59 years) with abdominal obesity participated in this cross-sectional study. Abdominal obesity was defined as a waist circumference ≥90 cm. Arterial stiffness was derived from brachial/ankle pulse wave velocity (baPWV). A treadmill exercise test was conducted to directly assess CRF using the peak oxygen uptake. Blood glucose, blood pressure, lipids, C-related protein (CRP), and baPWV were measured at rest. RESULTS: CRF was inversely associated with baPWV (r = -0.340, P = 0.014) and CRP level (r = -0.325, P = 0.026). In addition, high CRF was associated with a lower triglyceride level (r = -0.219, P = 0.030) and a higher high-density lipoprotein cholesterol level (r = 0.317, P = 0.019). CONCLUSIONS: These results demonstrated that high CRF was inversely associated with arterial stiffness in men with abdominal obesity. These results suggest that maintaining a high level of CRF can help middle-aged men with abdominal obesity to improve blood factors related to CVD.