October 1, 1989Journal of Biological ChemistryOpen Access

Allele-specific Expression of the Murine Ren-1 Genes

Q: What is the clinical evidence from this study?

Study design: Other. Intervention: Ren-1c and Ren-1d alleles. Primary outcome: Allele-specific expression patterns of Ren-1 genes in extra renal tissues.

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Key result

Allele-specific expression patterns observed for the Ren-1 genes in extra renal tissues of mice are regulated by closely associated sequences in cis.

Authors

JFJohn R. FabianRoswell Park Comprehensive Cancer Center LFLoren J. FieldUniversity of North Carolina at Chapel Hill RMRoss McGowanAmazon (United States)

Discussion

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Implication

May refine renin locus models in mice; leaves open human RAAS translation.

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Exposure / Comparator

Ren-1c and Ren-1d alleles

Primary Outcome

Allele-specific expression patterns of Ren-1 genes in extra renal tissues

Cite This Study

Fabian et al. (1989) studied this question. Ren-1c and Ren-1d alleles was evaluated on Allele-specific expression patterns of Ren-1 genes in extra renal tissues. Allele-specific expression patterns observed for the Ren-1 genes in extra renal tissues of mice are regulated by closely associated sequences in cis.

synapsesocial.com/papers/6a657e6dd0b9f96261fe5867 https://doi.org/10.1016/s0021-9258(18)71532-9

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Allele-specific Expression of the Murine Ren-1 Genes

Discussion

Member takes

Implication

PICO

Cite This Study

Allele-specific Expression of the Murine Ren-1 Genes

Discussion

Member takes

Implication

PICO

Cite This Study

Also Consider

Also Consider