Key result
An early increase in mean platelet volume after admission was independently associated with total mortality at 1 year in patients with NSTEMI (OR 1.84; 95% CI 1.28-2.65; P=0.001).
Why the study?
Does an early increase in mean platelet volume predict total mortality in patients with NSTEMI?
Population
400 patients with non-ST-segment elevation myocardial infarction
Design
Cohort
Follow-up
1 year
Authors
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MPV change may predict NSTEMI mortality; hypothesis-generating and requires prospective validation before clinical use.
Cohort (n=400)
Does an early increase in mean platelet volume predict total mortality in patients with NSTEMI?
Odds Ratio: 1.84 (95% CI 1.28–2.65)
p-value: p=0.001
An early increase in mean platelet volume within 24 hours of admission is an independent predictor of 1-year mortality in patients with NSTEMI, suggesting these patients may require more intensive antiplatelet therapy.
Kırış et al. (2016) conducted a cohort in Non-ST-segment elevation myocardial infarction (NSTEMI) (n=400). Change in mean platelet volume (ΔMPV) was evaluated on Total mortality at 1-year follow-up (OR 1.84, 95% CI 1.28-2.65, p=0.001). An early increase in mean platelet volume after admission was independently associated with total mortality at 1 year in patients with NSTEMI (OR 1.84; 95% CI 1.28-2.65; P=0.001).
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