Prognostic characteristics of cardiopulmonary exercise testing in heart failure: comparing American and European models
Key result
Bicycle ergometry and treadmill CPET yielded similar optimal prognostic thresholds for peak VO2 (12.9 vs 12.0 ml/kg/min) and VE/VCO2 slope (34.4 vs 34.5) for 1-year cardiac mortality in heart failure.
Why the study?
Does the mode of exercise (bicycle vs treadmill) impact the prognostic utility of CPET responses in patients with heart failure?
Population
207 subjects with heart failure
Comparison
Maximal cardiopulmonary exercise testing using… vs Maximal cardiopulmonary exercise testing using…
Design
Cohort
Follow-up
1 year
Authors
Discussion
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Member takes
Implication
Supports modality-agnostic CPET thresholds in HF; leaves open prospective validation before guideline changes.
Study Design
Type
Cohort (n=207)
Multicenter
Yes
Structured PICO
Does the mode of exercise (bicycle vs treadmill) impact the prognostic utility of CPET responses in patients with heart failure?
P
Population
207 subjects with heart failure who underwent maximal exercise CPET using either bicycle ergometry or treadmill, followed for 1 year for cardiac-related mortality.
E
Exposure
Maximal cardiopulmonary exercise testing (CPET) using bicycle ergometry
C
Comparator
Maximal cardiopulmonary exercise testing (CPET) using treadmill
O
Outcome
Cardiac-related mortality over a 1-year periodhard clinical
The prognostic utility of CPET in heart failure is comparable between bicycle ergometry and treadmill testing, supporting the global application of prognostic guidelines irrespective of testing modality.
Cite This Study
Arena et al. (2005) conducted a cohort in Heart failure (n=207). Bicycle ergometry CPET vs. Treadmill CPET was evaluated on 1-year cardiac-related mortality. Bicycle ergometry and treadmill CPET yielded similar optimal prognostic thresholds for peak VO2 (12.9 vs 12.0 ml/kg/min) and VE/VCO2 slope (34.4 vs 34.5) for 1-year cardiac mortality in heart failure.