Key result
An enhanced ventilatory response to exercise (VE/VCO2 slope ≥34) independently predicted death and cardiovascular hospitalization in elderly heart failure patients (HR 1.965; 95% CI 1.195-3.231).
Why the study?
Does cardiopulmonary exercise testing predict outcomes in elderly patients with heart failure?
Cohort (n=220)
Does cardiopulmonary exercise testing predict outcomes in elderly patients with heart failure?
Effect estimate: HR 1.965 (95% CI 1.195-3.231)
In elderly patients with heart failure, a steeper VE/VCO2 slope during cardiopulmonary exercise testing provides significant prognostic value for predicting death and cardiovascular hospitalizations.
No takes yet. Share an insight, caveat, or question.
May refine prognostication in elderly HF; leaves open incremental value and need for validation before practice change.
Scardovi et al. (2008) conducted a cohort in Heart failure (n=220). Cardiopulmonary exercise testing (CPET) was evaluated on Combined end point of death and hospital admission for worsening HF, arrhythmias or acute coronary syndromes (HR 1.965, 95% CI 1.195-3.231). An enhanced ventilatory response to exercise (VE/VCO2 slope ≥34) independently predicted death and cardiovascular hospitalization in elderly heart failure patients (HR 1.965; 95% CI 1.195-3.231).
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: