Key result
Plasma levels of IL-2 and sIL-2 receptor were significantly higher in patients with stable angina than in those with unstable angina or healthy controls.
Why the study?
Do plasma levels of IL-2 and sIL-2R differ between patients with stable angina, unstable angina, and healthy controls?
Population
105 patients presenting to the cardiac catheterization laboratory for coronary angiography or percutaneous…
Design
Cross-sectional
Authors
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May suggest distinct immune activation in stable angina; leaves open biomarker utility pending prospective validation.
Cross-Sectional (n=105)
Do plasma levels of IL-2 and sIL-2R differ between patients with stable angina, unstable angina, and healthy controls?
Plasma levels of IL-2 and sIL-2 receptor are significantly elevated in patients with stable angina compared to unstable angina or controls, suggesting a specific pattern of T-lymphocyte activation in stable ischemic heart disease.
Simon et al. (2001) conducted a cross-sectional in Ischemic heart disease (n=105). Stable angina vs. Unstable angina and healthy controls was evaluated on Plasma levels of interleukin-2 (IL-2) and soluble IL-2 receptor (sIL-2R). Plasma levels of IL-2 and sIL-2 receptor were significantly higher in patients with stable angina than in those with unstable angina or healthy controls.
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